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Consideraciones para los Pacientes Tratados con Celebrex



Consideraciones para los Pacientes Tratados con Celebrex


Celebrex

¤El uso de celecoxib concomitantemente con aspirina aumenta el riesgo para desarrollar toxicidad gastrointestinal en comparación con el uso de celecoxib como agente único.

†En pacientes con dolor moderado a severo después de la extracción del tercer molar.

**Tan rápido como a 22 minutos (la mediana del inicio de acción es alrededor de 30 minutos; rango: 22–33 minutos)

*AINE-ns: antiinflamatorio no esteroideo no selectivo

 

 

Referencias:

  1. WILNER, K. D. et al. (2002) Celecoxib does not affect the antiplatelet activity of aspirin in healthy volunteers. J Clin Pharmacol. 42 (9). p.1027-1030.
  2. CHAN, F. K. et al. (2010) Celecoxib versus omeprazole and diclofenac in patients with osteoarthritis and rheumatoid arthritis (CONDOR): A randomised trial. Lancet.[Online] p.1-7. Available from: http://www.thelancet.com. [Accessed: 21st February 2013].
  3. CRYER, B. et al. (2013) GI-REASONS: a novel 6-month, prospective, randomized, open-label, blinded endpoint (PROBE) trial. Am J Gastroenterol. 108 (3). p.392-400.
  4. MALLEN, SR, ESSEX MN, ZHANG R. Gastrointestinal tolerability of NSAIDs in elderly patients: a pooled analysis of 21 randomized clinical trials with celecoxib and nonselective NSAIDs. Curr Med Res Opin. 2011;27(7):1359-1366.
  5. CHEUNG, R., KRISHNASWAMI, S., KOWALSKI, K. (2007) Analgesic efficacy of celecoxib in postoperative oral surgery pain: a single-dose, two-center, randomized, double-blind,activeand placebo-controlled study. Clin Ther. 29. p.2498-2510.
  6. LEESE, P. T. et al. (2000) Effects of celecoxib, a novel cyclooxygenase-2 inhibitor, on platelet function in healthy adults: a randomized, controlled trial. J Clin Pharmacol. 40 (2). p.124-132.
  7. SCHROER, W. et al. (2011) Benefits of prolonged postoperative cyclooxygenase-2 inhibitor administration on total knee arthroplasty recovery. J Arthroplasty. 26 (6 Suppl. 1). p.2-7.
  8. PETRI, M. et al. (2004) Celecoxib effectively treats patients with acute shoulder tendinitis/bursitis. J Rheumatol. 31. p.1614-1620.
  9. WHITE, P. F. et al. (2007) Effect of short-term postoperative celecoxib administration on patient outcome after outpatient laparoscopic surgery. Can J Anaesth. 54 (5). p.342-348.
  10. CARDENAS-ESTRADA, E. et al. (2009) Efficacy and safety of celecoxib in the treatment of acute pain due to ankle sprain in a Latin American and Middle Eastern population. J Int Med Res. 37. p.1937-1951.
  11. MARTÍN-MOLA, E. et al. (2005) Celecoxib is as effective as ibuprofen in treating pain associated with osteoarthritis of the knee. Ann Rheum Dis. 64 (Suppl III). p.495.
  12. STRAND, V. et al. (2011) Treatment of osteoarthritis with continuous versus intermittent celecoxib. J Rheumatol. 38. p.2625-2634.
  13. EMERY, P. et al. (1999) Celecoxib versus diclofenac in long-term management of rheumatoid arthritis: randomised double-blind comparison. Lancet. 354: p.2106-2111.
  14. SIMON, L. S. et al. (1999) Anti-inflammatory and upper gastrointestinal effects of celecoxib in rheumatoid arthritis: a randomized controlled trial. JAMA. 282 (20): p.1921-1928.
  15. RALHA, L. et al. (2008) Efficacy and tolerability of celecoxibversus diclofenac: results of a multicenter, randomized, double-blind, non-inferiority study in subjects with acute low back pain. Revista Brasileira de Medicina. 65 (11). p.378-387.
  16. Información para Prescribir Celebrex ® 200 mg CÁPSULA versión CDS 16.0

 

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