
The treatment of rheumatoid arthritis is fraught with unknowns. It is not always certain how active the patient’s arthritis may be, even while they are engaged in an effective treatment regimen. What factors may predict a flare of the disease and how to confirm that the patient remains in remission are unknown.
PP-PPF-GLB-0342
The first consensus recommendations on the topic aim to address variation in diagnosis at the international, national, and local levels.
Sponsoring Organization: World Brain Death Project, assisted by international professional societies including the World Federation of Intensive and Critical Care, World Federation of Pediatric Intensive and Critical Care Societies, World Federation of Neurology, World Federation of Neurosurgery, and the World Federation of Critical Care Nurses.
PP-CNS-GLB-1691
In a small study, two measures of retinal thickness showed greater thinning rates and correlations with cognitive decline in patients with PD than in controls.
Increasing interest has focused on the development of biomarkers capable of tracking Parkinson disease (PD) progression over time.
PP-UOP-GLB-0099
A strong relationship was seen in both women and men, irrespective of the presence of PFO.
Previous studies have evaluated some of the complex relationships among cryptogenic stroke, migraine, and patent foramen ovale (PFO) and suggested the following: Migraine is associated with ischemic stroke, migraine with aura is associated with the presence of PFO, and the association between mi-graine and cryptogenic ischemic stroke is stronger among patients with PFO than without.
PP-CNS-GLB-1694
A new guideline recommends ultrasound instead of computed tomography for some patients with this finding.
How should we evaluate asymptomatic microscopic hematuria? A 2012 guideline from the American Urological Association (AUA) recommended that all patients older than 35 with microscopic hema-turia — defined by the AUA as ≥ 3 red cells per high-power field — should undergo both computed tomography urography (CTU) and cystoscopy.
PP-MHP-GLB-0171
Safety and Efficacy of Extreme Blood Pressure Lowering in Intracerebral Hemorrhage
Higher rates of neurologic deterioration and adverse events were associated with intensive treatment in patients with excessively high initial systolic blood pressure. Many patients with intracerebral hemorrhage (ICH) present with elevated systolic blood pressure (SBP). At times, SBP can be markedly elevated (>220 mm Hg).
PP-CNS-GLB-1605
A 45-year longitudinal study shows that mental illness is astonishingly common and that it’s better to be a “lumper” than a “splitter” when thinking diagnostically.
Cross-sectional epidemiological surveys have documented high rates of lifetime psychiatric disorders (about 40%–50%) and substantial comorbidity,
PP-CNS-GLB-1625
A retrospective analysis of cases shows that smooth meningeal thickening provides an additional diagnostic clue differentiating POEMS syndrome from chronic immune demyelinating polyneuropathy.
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin lesions) is a rare but treatable paraneoplastic disorder of plasma cells associated with sensorimotor polyneuropathy,
PP-CNS-GLB-1624
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