Noticias
Outcomes Are Worse in STEMI Patients Without Traditional Cardiovascular Risk Factors
Jueves, Julio 8, 2021
An analysis of Swedish registry data showed STEMI patients without cardiovascular risk factors — particularly women — experienced higher mortality.
Some patients who present with ST-segment elevation myocardial infarction (STEMI) do not have a history of standard modifiable cardiovascular risk factors (SMuRFs).
PP-CVP-GLB-0479
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Blood Transfusion Strategy in Patients with Acute Myocardial Infarction
Martes, Junio 22, 2021
A randomized trial showed that a more-restrictive strategy was noninferior.
In previous large randomized trials, restrictive transfusion strategies benefited patients with anemia, but those trials excluded patients with acute myocardial infarction (MI).
PP-CVP-GLB-0470
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Nonclassic TIA Symptoms and Stroke Risk
Martes, Junio 22, 2021
Both classic and nonclassic symptoms of transient ischemic attack confer similar 90-day stroke risk.
The short-term risk for stroke after transient ischemic attack (TIA) is high, and urgent evaluation and treatment can reduce this risk. However, since TIA can present with a broad range of neurologic symptoms, when symptoms could be consistent with but are not classic for TIA,
PP-CNS-GLB-1810
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Can Antioxidants Affect Risk for Parkinson Disease?
Martes, Junio 22, 2021
Vitamins E and C may be associated with risk, but the evidence remains limited.
To determine whether risk for future Parkinson disease (PD) diagnosis was reduced with increased dietary antioxidant intake and total nonenzymatic antioxidant capacity (NEAC), researchers examined data from 43,865 men and women (aged 18–94 at baseline) in the Swedish National March Cohort linked to the National Health Registries.
PP-CNS-GLB-1808
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The Alzheimer Disease Conversion-Related Pattern Score as Neurodegeneration Biomarker
Miércoles, Junio 16, 2021
An ADCRP score may be useful in identifying those with mild cognitive impairment who have underlying Alzheimer disease.
To create a biological definition of Alzheimer disease (AD), the amyloid-tau-neurodegeneration (ATN) classification scheme has been developed. Researchers in this study assessed the validity of an AD conversion related pattern (ADCRP) score as a biomarker for ATN in 269 participants with mild cog-nitive impairment (MCI).
PP-CNS-GLB-1779
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Life expetancy after bariatric surgery
Martes, Junio 8, 2021
Obesity is associated with increases in life-threatening diseases and premature mortality. Bariatric surgery leads to durable weight loss and reduces the risk for cardiovascular disease, type 2 diabetes, cancer, and all-cause death. The effect of bariatric surgery on life expectancy, however, has not been well defined.
PPP-IMU-GLB-0112
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Endovascular thrombectomy in stroke
Lunes, Mayo 31, 2021
Endovascular thrombectomy (EVT) has become an important treatment for patients with acute ischemic stroke who can be treated within 6 hours of stroke onset, and was one focus of a recent guideline update from the American Heart Association/American Stroke Association.
PP-CNS-GLB-1777
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Prevention of Early Ventilator-Associated Pneumonia after Cardiac Arrest
Lunes, Mayo 31, 2021
Major advances in the care of cardiac arrest patients have been reported in the literature over the past decade, including better data on pharmacologic and airway management during the intra-cardiac arrest period and after return of spontaneous circulation. The collection of articles presented here highlights some of those advances.
PP-IMU-GLB-0115
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Lung Cancer Screening
Domingo, Mayo 30, 2021
The Holy Grail in oncology is prevention against cancer ever occurring or detection early enough that curative treatment can be implemented. Lung cancer is the leading cause of cancer-related death, and with close to 1 billion active smokers worldwide, screening for lung cancers generates high interest and hope of early detection. Several prior large-scale studies of chest radiography for lung cancer screening failed to demonstrate improvements in mortality,
PP-IMU-GLB-0116
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Psychodynamic Psychotherapy for Functional Somatic Complaints
Domingo, Mayo 30, 2021
Short-term psychodynamic psychotherapy focusing on awareness and processing of emotionally laden material can be helpful for somatization.
Is psychodynamic psychotherapy still relevant? Researchers addressed this question in a meta-analysis of 17 randomized, controlled trials involving 2004 patients (mean age, 43) with disorders characterized by functional somatic complaints such as irritable bowel syndrome, fibromyalgia, and chronic pain disorders.
PP-CNS-GLB-1778
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Post-stroke therapy and prevention
Domingo, Mayo 30, 2021
Despite the fact that stroke is a leading cause of disability among adults, there has been a shortage of high-quality studies to address such important issues as management of stroke risk factors. Well-documented risk factors include hypertension, diabetes mellitus, and hyperlipidemia.
PP-CVP-GLB-0454
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Hip Fracture Care: A Step in the Right Direction
Domingo, Mayo 30, 2021
A quality-improvement intervention was associated with outcome successes.
Fragility hip fractures, often caused by a fall from standing height, portend substantial morbidity and mortality. Yale researchers implemented a multidisciplinary, multicomponent intervention designed to improve hip-fracture outcomes.
PP-PPF-GLB-0379
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Cardiovascular Risks During the Menopause Transition
Viernes, Mayo 21, 2021
This scientific statement provides a comprehensive review of the data linking the menopause transition to cardiovascular risk.
Sponsoring Organization: American Heart Association Background and Objective The menopause transition (MT) occurs when menstrual cycles become variable or other menopauserelated symptoms begin and is separated into seven stages with varying duration, hormone levels, and symptoms. This statement highlights the adverse cardiometabolic changes in women during the MT and suggests possible interventions.
PP-CVP-GLB-0451
Is Stroke Risk in Patients with Transient Ischemic Attack Decreasing?
Viernes, Mayo 21, 2021
Data from the Framingham Study suggest that modern medical treatment helps.
Transient ischemic attacks (TIAs) are a well-recognized precursor to a potential ischemic stroke.
PP-CNS-GLB-1768
Diagnosing And Predicting Development Of Rheumatoid Arthritis
Viernes, Marzo 26, 2021
The treatment of rheumatoid arthritis is fraught with unknowns. It is not always certain how active the patient’s arthritis may be, even while they are engaged in an effective treatment regimen. What factors may predict a flare of the disease and how to confirm that the patient remains in remission are unknown.
PP-PPF-GLB-0342
Determination of Brain Death/Death by Neurological Criteria: The World Brain Death Project
Viernes, Marzo 26, 2021
The first consensus recommendations on the topic aim to address variation in diagnosis at the international, national, and local levels.
Sponsoring Organization: World Brain Death Project, assisted by international professional societies including the World Federation of Intensive and Critical Care, World Federation of Pediatric Intensive and Critical Care Societies, World Federation of Neurology, World Federation of Neurosurgery, and the World Federation of Critical Care Nurses.
PP-CNS-GLB-1691
Benefits Of Metabolic Surgery
Viernes, Marzo 26, 2021
A plethora of studies comparing the metabolic benefits of bariatric surgery with usual medical management of obese patients has increased the focus on surgical management — either Roux-en-Y gastric bypass or, increasingly often, sleeve gastrectomy.
PP-IMU-GLB-0085
Can Retinal Thickness Predict Cognitive Decline in Parkinson Disease?
Viernes, Marzo 26, 2021
In a small study, two measures of retinal thickness showed greater thinning rates and correlations with cognitive decline in patients with PD than in controls.
Increasing interest has focused on the development of biomarkers capable of tracking Parkinson disease (PD) progression over time.
PP-UOP-GLB-0099
Association Between Migraine with Aura and Cryptogenic Ischemic Stroke in the Young
Viernes, Marzo 26, 2021
A strong relationship was seen in both women and men, irrespective of the presence of PFO.
Previous studies have evaluated some of the complex relationships among cryptogenic stroke, migraine, and patent foramen ovale (PFO) and suggested the following: Migraine is associated with ischemic stroke, migraine with aura is associated with the presence of PFO, and the association between mi-graine and cryptogenic ischemic stroke is stronger among patients with PFO than without.
PP-CNS-GLB-1694
Guidance in Evaluation of Microscopic Hematuria
Viernes, Marzo 26, 2021
A new guideline recommends ultrasound instead of computed tomography for some patients with this finding.
How should we evaluate asymptomatic microscopic hematuria? A 2012 guideline from the American Urological Association (AUA) recommended that all patients older than 35 with microscopic hema-turia — defined by the AUA as ≥ 3 red cells per high-power field — should undergo both computed tomography urography (CTU) and cystoscopy.
PP-MHP-GLB-0171
Amyloid Burden: A Reason for Poor Antidepressant Response in Late-Life Depression?
Lunes, Marzo 1, 2021
In cognitively intact individuals with late-life depression, cortical amyloid burden predicted poor antidepressant response.
Accumulation of cortical amyloid-β (Aβ) has been associated with greater depressive symptoms in cognitively intact older adults.
PP-CNS-GLB-1627
Safety and Efficacy of Extreme Blood Pressure Lowering in Intracerebral Hemorrhage
Lunes, Marzo 1, 2021
Safety and Efficacy of Extreme Blood Pressure Lowering in Intracerebral Hemorrhage
Higher rates of neurologic deterioration and adverse events were associated with intensive treatment in patients with excessively high initial systolic blood pressure. Many patients with intracerebral hemorrhage (ICH) present with elevated systolic blood pressure (SBP). At times, SBP can be markedly elevated (>220 mm Hg).
PP-CNS-GLB-1605
Psychiatric Disorders Across the Life Span: A Unitary Psychopathology Factor Best Fits the Data
Lunes, Marzo 1, 2021
A 45-year longitudinal study shows that mental illness is astonishingly common and that it’s better to be a “lumper” than a “splitter” when thinking diagnostically.
Cross-sectional epidemiological surveys have documented high rates of lifetime psychiatric disorders (about 40%–50%) and substantial comorbidity,
PP-CNS-GLB-1625
POEMS Syndrome: Clinical Features and Outcomes in a U.K. Cohort
Lunes, Marzo 1, 2021
A retrospective analysis of cases shows that smooth meningeal thickening provides an additional diagnostic clue differentiating POEMS syndrome from chronic immune demyelinating polyneuropathy.
POEMS syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammopathy, and skin lesions) is a rare but treatable paraneoplastic disorder of plasma cells associated with sensorimotor polyneuropathy,
PP-CNS-GLB-1624